What Lessons Have We Learned About GLP-1s?

Losing weight is hard. Very hard. Indeed, research suggests that only around 20 per cent of people who intentionally lose a significant amount of weight through dieting manage to keep it off for at least a year.

However, the emergence of glucagon-like peptide-1 (GLP-1) receptor agonist drugs has made this battle easier. By dramatically reducing people’s hunger drive, these drugs have made substantial weight loss achievable for the estimated 40 million adult users in the US.

Few medicines have transformed public health this quickly. Within just a few years of GLP-1 drugs becoming mainstream, the US adult obesity rate has begun to fall for the first time since records began.

Excerpted from BBC Science Focus

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